Knee pain can have multiple causes. The pain can be due to soft tissue damage such as muscle strain, ligament strain, or meniscal injury. The pain can also be due to bone or joint degeneration leading to arthritic pain. Imaging with X-ray or MRI may be ordered to help further clarify the cause of the pain. Once the cause is known, your physician can help guide your treatment process, which may include medications, physical therapy, or surgical consultation. For arthritic bone pain, the therapy regimen may include medications, steroid injections, hyaluronic acid injections, PRP and stem cell injections. Each treatment option has positives and negatives and so it is important to clearly understand all your treatment options.